A New Path for
Depression Care.
A medically supervised prescription option for adults with treatment-resistant depression, designed to help reduce depressive symptoms and support meaningful progress in your mental health.
Understanding SPRAVATO®
SPRAVATO® is an FDA-approved, intranasal esketamine treatment for adults with treatment-resistant depression. It works differently than traditional antidepressants and is administered in a REMS-certified setting under the supervision of a healthcare professional.
Whether SPRAVATO® is right for you is determined through a comprehensive medical evaluation, including a review of your treatment history, current symptoms, and overall health.
Your SPRAVATO® Experience at Renova
A structured, supportive process with careful medical oversight at every step.
1. Consultation &
Screening
A thorough medical evaluation to confirm your diagnosis, review treatment history, and determine if SPRAVATO® may be appropriate for you.
2. Personalized
Treatment Plan
A care plan tailored to your needs, including treatment frequency and ongoing assessment of your progress.
3. Supervised
Administration
You self-administer SPRAVATO® (nasal spray) at our clinic, with support and supervision from our healthcare team.
4. Monitoring &
Follow-Up
You’ll be monitored for at least 2 hours after each treatment, with regular follow-up to assess response, manage any side effects, and adjust your plan.
Is SPRAVATO® Right for You?
SPRAVATO® may be an option for adults with treatment-resistant depression, when previous antidepressant treatments have not provided enough relief.
Frequently Asked Questions
Get answers to common questions about SPRAVATO®, the treatment process, safety, and what to expect at Renova.
How does SPRAVATO® work?
SPRAVATO® contains esketamine, a prescription nasal spray that affects glutamate signaling in the brain differently from many conventional antidepressants. Your prescriber can explain potential benefits and risks in the context of your treatment history.
What happens during treatment?
After clinical screening and treatment planning, you self-administer the nasal spray at a certified healthcare setting under professional supervision. Staff monitor you during and after the treatment session.
How long is the monitoring period?
You are monitored for at least two hours after each treatment. Your healthcare team will assess when it is appropriate for you to leave, and you must arrange transportation home rather than driving yourself.
How is SPRAVATO® different from KAP?
SPRAVATO® is an FDA-approved esketamine nasal spray administered under specific clinical and monitoring requirements. Ketamine-Assisted Psychotherapy (KAP) incorporates psychotherapy around ketamine treatment; its medical protocols and regulatory status differ.
Take the Next Step With Renova
If you are interested in learning more about SPRAVATO® and whether it may be right for you, we invite you to schedule a consultation. Our team will answer your questions, discuss your treatment history and goals, and help you make an informed decision about your care.